DescriptionQuantum computing is a quickly growing field and we expect viable systems to be available relatively soon. However, it’s becoming clear that quantum computing systems alone are only of limited use unless integrated with HPC systems to enable both efficient pre- and post-processing and to allow for truly hybrid applications. Many questions remain: which applications will benefit from such acceleration? How widely will quantum acceleration be efficient and cost-effective? How large do quantum systems have to be to make an impact and when will this be the case? What is the impact on the operation in HPC centers? Will quantum acceleration augment or replace other accelerators, e.g., for AI? Or will the quantum computing hype bubble just pop? In this panel, we will discuss these questions with experts from the quantum computing community, with HPC architects, representatives from HPC centers as well as vendors of traditional and emerging accelerators.